Topic: Conservative vs regenerative endodontics – from animal studies to clinical trials
Abstract
Regenerative endodontics emerged more than ten years ago. Because it is a new science, much confusion has come along with it. As of today, based on all the available data published, we have not been practicing “regenerative endodontics”. Therefore, the term “regenerative endodontics” should be changed and better defined. This presentation will clarify what “regenerative endodontics” should really represent. The current so-called “revitalization” treatment should be categorized as “conservative endodontics”. The “revascularization” term should no longer be used and only to represent trauma avulsion cases after replantation. On the other hand, stem-cell based therapy research has shown convincing data suggesting potential practice of true “regenerative endodontics” in the future. This presentation will provide an updated review on the rapid progress of stem-cell based “regenerative endodontics” research from small animal studies to large animal validation and eventually to human clinical trials. The potential of “conservative endodontics” to one day reaching “regenerative endodontics” will be analyzed and discussed.
| CPD Accreditation CPD-0220-20 | 1.5 CPD Points |
Learning objectives
At conclusion, participants should be able to:
- Describe the definition of “conservative endodontics.”
- Describe the definition of “regenerative endodontics.”
- Describe the progress of “regenerative endodontics” in humans.
Meet the speaker
Professor George T.-J. Huang, DDS, MSD, DSc
Dr. Huang is a board certified endodontist, currently Professor and former Director for Stem Cells and Regenerative Therapies, Department of Bioscience Research at UTHSC, College of Dentistry. He is the former Chair/Herbert Schilder Professor in Endodontics, at Boston University, also a former Chair in Endodontics at Columbia University.
Dr. Huang has published ~180 research articles, abstracts, review articles, including papers in Stem Cells, Stem Cells and Development, Stem Cell Research and Therapy, Stem Cell Reviews and Reports, Tissue Engineering, Regenerative Medicine, Infection and Immunity, Human Gene Therapy, Journal of Dental Research, Journal of Endodontics, etc; and 19 book chapters in books such as Ingle’s Endodontics, Cohen’s Pathways of the Pulp, Endodontic Microbiology, Principles of Regenerative Medicine, Tissue Engineering and Regenerative Dentistry, Tissue-Specific Stem Cell Niche, Material-Tissue Interfacial Phenomena, etc; and co-edited with Dr. Irma Thesleff and wrote chapters for the text book “Stem cells, craniofacial development and regeneration”, in 2013, published by Wiley-Blackwell. His research has been funded by various sources including NIH and AAE Foundation. His current research interest is in the area of stem cells and regenerative medicine. Distinguished Scientist Award, IADR, 2015.